Fujimoto Naohiro
   Department   School of Medicine  Urology, Clinical Medical Sciences
Article types journal article
Language English
Peer review Peer reviewed
Title Efficacy and Tolerability of Bacillus Calmette-Guérin Therapy as the First-Line Therapy for Upper Urinary Tract Carcinoma In Situ.
Journal Formal name:Cancer investigation
Abbreviation:Cancer Invest
ISSN code:15324192/07357907
Domestic / ForeginForegin
Volume, Issue, Page 36(2),152-157頁
Author and coauthor Tomisaki Ikko, Kubo Tatsuhiko, Minato Akinori, Fujimoto Naohiro
Publication date 2018/02
Summary There are few data on Bacillus Calmette-Guérin (BCG) therapy for upper urinary tract carcinoma in situ (UUT CIS). We retrospectively evaluated the efficacy and tolerability of BCG therapy for 41 patients [52 renal units(RUs)] with UUT CIS. Of 52 RUs, complete response was achieved in 47 (90%). The 5-year recurrence-, progression-free survival rates were 60.2% and 74.2%, respectively. Adverse events were observed in 31 (76%) patients, but most of them were mild. The scheduled instillations were completed in 31 (74%) of 42 patients. Our results demonstrated that BCG therapy for UUT CIS was satisfactory with high efficacy and tolerability.
DOI 10.1080/07357907.2018.1430815
PMID 29393701