Fujimoto Naohiro
   Department   School of Medicine  Urology, Clinical Medical Sciences
Article types journal article
Language English
Peer review Peer reviewed
Title Demographics, management and treatment outcomes of benign and malignant retroperitoneal tumors in Japan.
Journal Formal name:International journal of urology : official journal of the Japanese Urological Association
Abbreviation:Int J Urol
ISSN code:14422042/09198172
Domestic / ForeginForegin
Volume, Issue, Page 25(1),61-67頁
Author and coauthor Fujimoto Naohiro, Kubo Tatsuhiko, Hisaoka Masanori, Udo Kazuma, Yokomizo Akira, Shibuya Tadamasa, Wakeda Hironobu, Nishihara Kiyoaki, Moriya Ryosuke, Iwakuma Keiko,
Publication date 2017/10
Summary OBJECTIVES:To show the demographics, type of treatment and clinical outcomes of patients with retroperitoneal tumors in Japan.METHODS:We carried out a retrospective analysis of patients with retroperitoneal tumors treated between 2000 and 2012 at 12 university hospitals in Japan. Histology was re-evaluated using the 2013 World Health Organization classification.RESULTS:A total of 167 patients were included in the analysis. The number of diagnosed patients increased over the 12-year study period. Liposarcoma and schwannoma were the most common histological types among intermediate/malignant and benign tumors, respectively. The intermediate/malignant tumors were larger and were more frequently found in older people. Surgical resection was the primary treatment for 151 patients. The median survival duration for patients with malignant tumors was 91 months, and was significantly shorter than that for patients with benign and intermediate tumors (P < 0.01). R2 resection was associated with significantly shorter survival than R0/R1 resection for malignant tumors (P < 0.01), but not for intermediate. Grossly complete resection of the recurrent tumors improved survival.CONCLUSION:The number of patients diagnosed with retroperitoneal tumors increased over time. R2 resection of primary tumors was found to be associated with poor prognosis in malignant tumors, but not in intermediate tumors. Complete surgical resection of recurrent tumors was associated with a better oncological outcome.
DOI 10.1111/iju.13469
PMID 28994196