Fujimoto Naohiro
   Department   School of Medicine  Urology, Clinical Medical Sciences
Article types journal article
Language English
Peer review Peer reviewed
Title SLCO1B1, SLCO2B1, and SLCO1B3 polymorphisms and susceptibility to bladder cancer risk.
Journal Formal name:Cancer investigation
Abbreviation:Cancer Invest
ISSN code:15324192/07357907
Volume, Issue, Page 32(6),256-61頁
Author and coauthor Bui Hoai Thi Thu, Fujimoto Naohiro, Kubo Tatsuhiko, Inatomi Hisato, Matsumoto Tetsuro
Publication date 2014/07
Summary A variety of carcinogens are excreted in urine and may be actively transported by organic anion-transporting polypeptides that encoded by SLCOs. In this study, we evaluated whether single nucleotide polymorphisms (SNPs) in SLCO1B1, SLCO2B1, and SLCO1B3 are associated with bladder cancer susceptibility. Our results, for the first time, indicated that polymorphisms of SLCO1B1 rs2306283 might be associated with bladder cancer risk. Therefore, SNPs in SLCO1B1 may be potential biomarkers for assessing the risk of bladder cancer.
DOI 10.3109/07357907.2014.907421
PMID 24762081