モリタ ヒロミ
  守田 弘美
   所属   産業医科大学病院  診療科 小児科
   職種   助教
論文種別 症例報告
言語種別 英語
査読の有無 査読あり
表題 Pulmonary and pleural metastasis of intracranial anaplastic meningioma in a 3-year-old boy: A case report.
掲載誌名 正式名:Molecular and clinical oncology
略  称:Mol Clin Oncol
ISSNコード:20499450/20499450
掲載区分国外
巻・号・頁 7(4),633-636頁
著者・共著者 ◎Honda Yuko, Shirayama Rie, Morita Hiromi, Kusuhara Koichi
発行年月 2017/10
概要 In adults, meningiomas occasionally display aggressive behavior and may occasionally metastasize. By contrast, pediatric meningiomas are rare, and there is limited information regarding their clinical characteristics, treatment and prognosis. We herein report the case of a 3-year-old boy with anaplastic meningioma with a history of local recurrence and late pulmonary metastasis. At diagnosis, a 70-mm mass lesion in was identified in the right frontal lobe, with intratumoral hemorrhage. The tumor was attached to the falx cerebri and was completely resected. The histological diagnosis was anaplastic meningioma, World Health Organization grade III. Two months after the surgery, the meningioma recurred at the same site. Although the patient received radiotherapy after a second operation, the tumor metastasized to the lung and pleura 8 months after the initial operation. The metastasis was resistant to treatment, even after gross total resection, and the effectiveness of further radiotherapy was limited. The patient succumbed to the disease 1 year and 4 months after the initial diagnosis. The findings of the present case and a review of the relevant literature suggest that recurrence and metastasis of meningiomas are difficult to predict. Therefore, such patients should be carefully monitored throughout the follow-up period.
DOI 10.3892/mco.2017.1375
PMID 29046796