Imanishi Naoko
   Department   University Hospital  General Thoracic Surgery, Clinical Departments
Article types journal article
Language English
Peer review Peer reviewed
Title Total or partial vertebrectomy for lung cancer invading the spine.
Journal Formal name:Annals of medicine and surgery (2012)
Abbreviation:Ann Med Surg (Lond)
ISSN code:/20490801
Domestic / ForeginForegin
Volume, Issue, Page 12,1-4頁
Author and coauthor Oka Soichi, Matsumiya Hiroki, Shinohara Shuichi, Kuwata Taiji, Takenaka Masaru, Chikaishi Yasuhiro, Hirai Ayako, Imanishi Naoko, Kuroda Koji, Yamada Sohsuke, Uramoto Hidetaka, Nakamura Eiichiro, Tanaka Fumihiro
Publication date 2016/12
Summary BACKGROUND:Surgery for lung cancer invading the spine remains challenging associated with high morbidity and mortality. However, recent advances in surgical techniques as well as in perioperative care may improve outcomes of lung cancer surgery with vertebrectomy. We describe our surgical approach and assess the outcome lung cancer invading the spine.METHODS:We retrospectively reviewed our recent experiences of lung cancer with vertebral invasion, in which we have performed total or partial vertebrectomy from January 2011 through April 2015.RESULTS:We experienced eight patients who were treated with partial or total vertebrectomy for lung cancer. Vertebral invasion was evaluated by chest CT and MRI findings. All cases were no distant metastasis. N factors were all patients N0 revealed by chest CT and PET-CT. Two patients were treated preoperative induction therapy (CDDP + TS-1, Radiation 50 Gy). For the surgery, total vertebrectomy was performed two patients, hemi vertebrectomy was two patients, transverse-process resection was four patients. In all of eight cases, complete resection were perfomed with total or partial vertebrectomy. Morbidity was observed in six patients (75%); no mortality occurred. Six patients (75%) were survived after surgery (range: 12-62 months) and four patients (50%) were no recurrence. Five years overall survival rate was 71.4%.CONCLUSIONS:In our experience, Lung cancer surgery combined with vertebrectomy is highly aggressive surgery associated with high morbidity. But, this procedure is a promising treatment option for selected patients, for example N0M0 disease with lung cancer invading the spine.
DOI 10.1016/j.amsu.2016.10.002
PMID 27790371