Imanishi Naoko
   Department   University Hospital  General Thoracic Surgery, Clinical Departments
   Position  
Article types case reports
Language English
Peer review Peer reviewed
Title Circulating Tumor Cells as an Indicator of Postoperative Lung Cancer: A Case Report.
Journal Formal name:The American journal of case reports
Abbreviation:Am J Case Rep
ISSN code:19415923/19415923
Domestic / ForeginForegin
Volume, Issue, Page 17,663-5頁
Author and coauthor Kuwata Taiji, Yoneda Kazue, Kobayashi Kenichi, Oyama Rintarou, Matumiya Hiroki, Shinohara Shuichi, Takenaka Masaru, Oka Soichi, Chikaishi Yasuhiro, Inanishi Naoko, Kuroda Koji, Tanaka Fumihiro
Publication date 2016/09
Summary BACKGROUND Circulating tumor cells (CTCs) are tumor cells that are shed from primary tumors and circulate in the peripheral blood. CTCs, as a surrogate of micro-metastasis, can be a useful clinical marker, but their clinical significance remains unclear in lung cancer. We now report a case of lung cancer in which the count of CTCs was useful in monitoring postoperative recurrence. CASE REPORT A 50-year-old man had undergone right upper lobectomy for lung cancer (pT1bN2M0, stage IIIA adenocarcinoma), followed by cisplatin-based adjuvant chemotherapy. After the patient's operation, we initiated monitoring of CTCs using CellSearch, and documented the change in the CTC count along with the development of cancer recurrence and response or progression to chemotherapy given for recurrent disease. CONCLUSIONS The CTC count may be useful in monitoring blood of patients with lung cancer.
PMID 27629545