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Nakano Yoshiteru
Department School of Medicine Neurosurgery, Clinical Medical Sciences Position |
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| Article types | journal article |
| Language | English |
| Peer review | Peer reviewed |
| Title | Clinical features and surgical management of intracranial meningiomas in the elderly. |
| Journal | Formal name：Oncology letters Abbreviation：Oncol Lett ISSN code：17921074/17921074 |
| Volume, Issue, Page | 14(1),909-917頁 |
| Author and coauthor | Yamamoto Junkoh, Takahashi Mayu, Idei Masaru, Nakano Yoshiteru, Soejima Yoshiteru, Akiba Daisuke, Kitagawa Takehiro, Ueta Kunihiro, Miyaoka Ryo, Nishizawa Shigeru |
| Publication date | 2017/07 |
| Summary | Meningioma accounts for ~25% of all primary intracranial neoplasms and the incidence increases with age. Prvios population-based studies demonstrated that the annual incidence of intracranial meningiomas was 1.2-3.1/100,000 population. In particular, the incidence of this disease among the elderly is high. Recently, increased life expectancy and greater use of diagnostic radiological imaging led to an increased incidence in the diagnosis of intracranial meningiomas, both symptomatic and asymptomatic, in the elderly. Thus, neurosurgeons may be increasingly confronted with the management of intracranial meningiomas in the elderly. In practice, it is often difficult for physicians to determine whether traditional surgical resection is the optimal management strategy for intracranial meningiomas in the elderly. However, reported clinical studies about the outcome of surgical resection of intracranial meningiomas in the elderly are limited. Increased risk of mortality and morbidity associated with surgical treatment for intracranial meningiomas in the elderly compared with younger patients have been controversial. In the present study, the clinical features of intracranial meningiomas in 70 consecutive intracranial meningioma patients that underwent surgical treatment at the affiliated hospital of University of Occupational and Environmental Health between 2007 and 2013 were assessed. In addition, patient selection and surgical management of intracranial meningioma in elderly patients was discussed. Preoperative factors, including symptoms, tumor location, tumor size, Karnofsky Performance Scale (KPS) score and American Society of Anesthesiology (ASA) score, and postoperative factors, including pathological diagnosis, tumor proliferation index (Ki-67), resection rate (Simpson grade), length of hospital stay and discharge destination were retrospectively analyzed in patients aged ≥75 years (n=16; elderly group) and <75 years (n=54; younger group). Outcomes were assessed |
| DOI | 10.3892/ol.2017.6174 |
| PMID | 28693251 |