Mori Masataka
   Department   University Hospital  General Thoracic Surgery, Clinical Departments
   Position  
Article types case reports
Language English
Peer review Peer reviewed
Title Primary epithelial-myoepithelial carcinoma of the lung with cavitary lesion: A case report.
Journal Formal name:Molecular and Clinical Oncology
Abbreviation:Mol Clin Oncol
Domestic / ForeginForegin
Volume, Issue, Page 9(3),315-317頁
Author and coauthor Masataka Mori, Takeshi Hanagiri, Ryoichi Nakanishi, Shuhei Ashikari, Manabu Yasuda, and Fumihiro Tanaka.
Publication date 2019/09
Summary Epithelial-myoepithelial carcinoma (EMC) typically arises in the salivary glands, whereas EMC of the lung is an extremely rare histological form that originates from the bronchial glands. Although cavitation in primary lung cancer is not uncommon, to the best of our knowledge, a case of EMC with a cavitary lesion has not been reported to date. We herein describe a case of cavity-forming pulmonary EMC. A 72-year-old man was referred to our department due to a thickened cystic wall discovered in the upper lobe of the left lung and underwent thoracoscopic left upper lobectomy. Microscopically, the tumor was characterized by biphasic architecture, with glands surrounded by myoepithelial cells. The pathological diagnosis was EMC. The patient has remained in good health for 2 years postoperatively, without any evidence of recurrence. As regards the mechanism of cavity formation, it was hypothesized that the bronchial gland in the primary cystic lesion had been present 3 years prior to the development of the EMC, and grew to become a cavitary lesion. Therefore, although the mechanism of cavity formation remains to be elucidated, EMC of the lung may include a cavitary lesion.
DOI 10.3892/mco.2018.1678
PMID 30155254