オオタニ マコト   Otani Makoto
  大谷 誠
   所属   関連施設  産業保健データサイエンスセンター 産業保健データサイエンスセンター
   職種   助教
論文種別 原著
言語種別 英語
査読の有無 査読なし
表題 Effect of dementia on outcomes of elderly patients with hemorrhagic peptic ulcer disease based on a national administrative database.
掲載誌名 正式名:Aging clinical and experimental research
略  称:Aging Clin Exp Res
ISSNコード:17208319/15940667
巻・号・頁 27(5),717-25頁
著者・共著者 Murata Atsuhiko, Mayumi Toshihiko, Muramatsu Keiji, Ohtani Makoto, Matsuda Shinya
発行年月 2015/10
概要 BACKGROUND:Little information is available on the effect of dementia on outcomes of elderly patients with hemorrhagic peptic ulcer disease at the population level.AIMS:This study aimed to investigate the effect of dementia on outcomes of elderly patients with hemorrhagic peptic ulcer based on a national administrative database.METHODS:A total of 14,569 elderly patients (≥80 years) who were treated by endoscopic hemostasis for hemorrhagic peptic ulcer were referred to 1073 hospitals between 2010 and 2012 in Japan. We collected patients' data from the administrative database to compare clinical and medical economic outcomes of elderly patients with hemorrhagic peptic ulcers. Patients were divided into two groups according to the presence of dementia: patients with dementia (n = 695) and those without dementia (n = 13,874).RESULTS:There were no significant differences in in-hospital mortality within 30 days and overall mortality between the groups (odds ratio; OR 1.00, 95 % confidence interval; CI 0.68-1.46, p = 0.986 and OR 1.02, 95 % CI 0.74-1.41, p = 0.877). However, the length of stay (LOS) and medical costs during hospitalization were significantly higher in patients with dementia compared with those without dementia. The unstandardized coefficient for LOS was 3.12 days (95 % CI 1.58-4.67 days, p < 0.001), whereas that for medical costs was 1171.7 US dollars (95 % CI 533.8-1809.5 US dollars, p < 0.001).CONCLUSIONS:Length of stay and medical costs during hospitalization are significantly increased in elderly patients with dementia undergoing endoscopic hemostasis for hemorrhagic peptic ulcer disease.
DOI 10.1007/s40520-015-0328-1
PMID 25708828